Saudi Press

Saudi Arabia and the world
Friday, Aug 22, 2025

Japanese researchers create a 'vaccine' against getting old

Japanese researchers create a 'vaccine' against getting old

Researchers at a Tokyo university say their vaccine slowed the ageing process in mice, and could even aid the treatment of ageing-related diseases.

What if you could live forever? It's a question long pondered by fictional supervillains and Silicon Valley billionaires alike.

Now researchers in Japan say they may have taken a step toward boosting human longevity with successful trials of a vaccine against the cells that contribute to the ageing process.

In laboratory trials, a drug targeting a protein contained in senescent cells - those which have naturally stopped reproducing themselves - slowed the progression of frailty in older mice, the researchers from Tokyo's Juntendo University said.

The vaccine also successfully targeted the senescent cells in fatty tissue and blood vessels, suggesting it could have a positive impact on other medical conditions linked to ageing.

"We can expect that (the vaccine) will be applied to the treatment of arterial stiffening, diabetes and other ageing-related diseases," Juntendo professor Toru Minamino told Japan's Jiji news agency.

What is cellular senescence?


Cells become senescent when they stop duplicating themselves, often in response to naturally-occurring damage to their DNA. Cellular senescence is thought to contribute to the ageing process itself, as well as ageing-related diseases like Alzheimer's and some cancers.

"Senescent cells secrete a series of factors that disrupt the function of the tissue," Dr Salvador Macip, head of the University of Leicester's Mechanisms of Cancer and Ageing Lab, told Euronews Next.

"They 'call' cells from the immune system, in theory to be cleared by them (but that eventually fails) and create a chronic low level inflammation, mixed with fibrosis," Macip said.

Macip was part of an international team of academics from universities in the UK, Spain, Nigeria and Saudi Arabia that published research on another method of tackling senescent cells in October this year.

"The biological process of ageing is very complex, therefore it is unlikely that one single strategy will completely stop it or reverse it. However, there are probably many ways to slow it down, and clearing senescent cells seems to be one of the easiest and potentially more effective," he said.

The limit on lifespan


In laboratory tests, preventing the build-up of senescent cells extended the lifespan of mice by 15 per cent, Macip told Euronews Next. Other, similar experiments have achieved as much as a 35 per cent increase, he said.

File photo. Similar experiments have reported up to a 35 per cent increase in the longevity of mice, Macip said


But before you get too excited, it's worth bearing in mind that researchers still don't know how much a living creature's lifespan can be extended.

"This is a very interesting question, and one that we still have not agreed upon. Some believe there is a 'hard' limit for human lifespan (around 130 years is the current estimate), while others think that, on paper, immortality should be feasible," Macip said.

"It's still early to know how much life can be extended and whether there's a limit or not".

We may not have to wait too long for an answer, though.

"The field of anti-ageing research is advancing very fast. In the last decade, there have been many key discoveries," Macip said.

"The person that will take the first anti-ageing pill has probably already been born".

Newsletter

Related Articles

Saudi Press
0:00
0:00
Close
Dogfights in the Skies: Airbus on Track to Overtake Boeing and Claim Aviation Supremacy
Tim Cook Promises an AI Revolution at Apple: "One of the Most Significant Technologies of Our Generation"
Are AI Data Centres the Infrastructure of the Future or the Next Crisis?
Miles Worth Billions: How Airlines Generate Huge Profits
Zelenskyy Returns to White House Flanked by European Allies as Trump Pressures Land-Swap Deal with Putin
Beijing is moving into gold and other assets, diversifying away from the dollar
Cristiano Ronaldo Makes Surprise Stop at New Hong Kong Museum
Zelenskyy to Visit Washington after Trump–Putin Summit Yields No Agreement
High-Stakes Trump-Putin Summit on Ukraine Underway in Alaska
Iranian Protection Offers Chinese Vehicle Shipments a Cost Advantage over Japanese and Korean Makers
Saudi Arabia accelerates renewables to curb domestic oil use
Cristiano Ronaldo and Georgina Rodríguez announce engagement
Asia-Pacific dominates world’s busiest flight routes, with South Korea’s Jeju–Seoul corridor leading global rankings
Private Welsh island with 19th-century fort listed for sale at over £3 million
Sam Altman challenges Elon Musk with plans for Neuralink rival
Australia to Recognize the State of Palestine at UN Assembly
The Collapse of the Programmer Dream: AI Experts Now the Real High-Earners
Armenia and Azerbaijan to Sign US-Brokered Framework Agreement for Nakhchivan Corridor
British Labour Government Utilizes Counter-Terrorism Tools for Social Media Monitoring Against Legitimate Critics
WhatsApp Deletes 6.8 Million Scam Accounts Amid Rising Global Fraud
Nine people have been hospitalized and dozens of salmonella cases have been reported after an outbreak of infections linked to certain brands of pistachios and pistachio-containing products, according to the Public Health Agency of Canada
Texas Residents Face Water Restrictions While AI Data Centers Consume Millions of Gallons
Tariffs, AI, and the Shifting U.S. Macro Landscape: Navigating a New Economic Regime
India Rejects U.S. Tariff Threat, Defends Russian Oil Purchases
United States Establishes Strategic Bitcoin Reserve and Digital Asset Stockpile
Thousands of Private ChatGPT Conversations Accidentally Indexed by Google
China Tightens Mineral Controls, Curtailing Critical Inputs for Western Defence Contractors
OpenAI’s Bold Bet: Teaching AI to Think, Not Just Chat
BP’s Largest Oil and Gas Find in 25 Years Uncovered Offshore Brazil
JPMorgan and Coinbase Unveil Partnership to Let Chase Cardholders Buy Crypto Directly
British Tourist Dies Following Hair Transplant in Turkey, Police Investigate
WhatsApp Users Targeted in New Scam Involving Account Takeovers
Trump Deploys Nuclear Submarines After Threats from Former Russian President Medvedev
Germany’s Economic Breakdown and the Return of Militarization: From Industrial Collapse to a New Offensive Strategy
IMF Upgrades Global Growth Forecast as Weaker Dollar Supports Outlook
Politics is a good business: Barack Obama’s Reported Net Worth Growth, 1990–2025
"Crazy Thing": OpenAI's Sam Altman Warns Of AI Voice Fraud Crisis In Banking
Japanese Prime Minister Vows to Stay After Coalition Loses Upper House Majority
President Trump Diagnosed with Chronic Venous Insufficiency After Leg Swelling
Man Dies After Being Pulled Into MRI Machine Due to Metal Chain in New York Clinic
FIFA Pressured to Rethink World Cup Calendar Due to Climate Change
"Can You Hit Moscow?" Trump Asked Zelensky To Make Putin "Feel The Pain"
Nvidia Becomes World’s First Four‑Trillion‑Dollar Company Amid AI Boom
Iranian President Reportedly Injured During Israeli Strike on Secret Facility
Kurdistan Workers Party Takes Symbolic Step Towards Peace in Northern Iraq
BRICS Expands Membership with Indonesia and Ten New Partner Countries
Elon Musk Founds a Party Following a Poll on X: "You Wanted It – You Got It!"
AI Raises Alarms Over Long-Term Job Security
Saudi Arabia Maintains Ties with Iran Despite Israel Conflict
Russia Formally Recognizes Taliban Government in Afghanistan
×