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Thursday, May 02, 2024

Innovative Patch Developed to Prevent Pain during Vaccine Injections

Scientists at the Institute for Precision Chemical Engineering, which is part of the Russian Technological University, have developed an innovative patch that prevents the sensation of pain during vaccine injections, according to a statement from the university’s media office. The patch employs micro-needles, each less than 0.6 mm in length, which can penetrate through the outer skin layer, the stratum corneum, without affecting nerve endings.
"This method of vaccine delivery is entirely painless and extremely effective. It is also psychologically more acceptable, particularly for children," the source explained. The patch, which contains a cluster of these dissolve-on-contact micro-needles, is projected to eventually replace traditional syringe injections. The needles are designed to dissolve after penetrating the skin within minutes or hours, depending on the composition. They are suitable for administering a wide range of vaccines and in some cases, allow for a lower antigen dose compared to traditional injection methods. These details were reported by the Russian newspaper "Izvestia."

To further elucidate, Stanislav Kudzh, the university president, mentioned, "Improving pharmaceutical technologies is an urgent task for modern science. Young scientists are working on projects that could substantially improve the lives of millions." He emphasized that "this patch is expected to become an integral part of the domestic pharmaceutical industry in the near future."

Kudzh revealed another project at the institute involving the production of oral strips containing small dissolvable drug tablets that are placed in the mouth cavity and quickly begin to dissolve and be absorbed. This method avoids harming the mucous membrane of the stomach and does not impact the pancreas. Additionally, it eliminates the need for patients to take the medication with water.

It is worth noting that this drug delivery method is suitable for a broad spectrum of medications. The efficacy of some drugs may be enhanced when administered through this method, compared to the traditional tablets which dissolve in the stomach or intestines.
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